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Beating Heart Disease

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Overview

Lipoproteins 

Heart Disease 

Case Study 

Frequently Asked Questions 

Glossary of Terms 



Resources for Health Care Professionals

Resources for Patients 

Glossary of Terms

Terms

ApoA1

ApoB

ApoE Genotype

Apolipoprotein A1

Apolipoprotein B

AspirinWorks®

C-Peptide

CYP2C19

F2-Isoprostanes

Factor V Leiden Genotype

Fibrinogen

Free Fatty Acid

HDL-P

High Sensitivity C-Reactive Protein

Homocysteine

Insulin

hsCRP

LDL-P

Lp-PLA2

Lp(a) Cholesterol

Lp(a) Mass

MPO

MTHRF

Myeloperoxidase

NT-proBNP

PLAC® Test

Prothrombin G20210A Mutation

RBC Folate

sdLDL

Small Dense LDL Cholesterol

Vitamin B12

Vitamin D


Definitions

Apolipoprotein A1 (ApoA1) the major protein component of HDL-C (good cholesterol) in your blood.

Apolipoprotein B (ApoB) helps "unlock" the door to cells and delivers cholesterol to the liver. If you have high levels of ApoB, it can lead to plaque that causes heart disease.

Apolipoprotein E (ApoE) Genotype plays a critical role in comprehensive measurements by helping to identify how people respond to varied amounts of dietary fat and how they carry cholesterol in the bloodstream.

AspirinWorks® Aspirin therapy has been reported to reduce cardiovascular events from 15% to 40%. However, Aspirin use is not without risk. We perform the AspirinWorks® test, a marker of platelet hyperactivity, to identify patients most likely to benefit from Aspirin.

C-Peptide is a naturally occurring substance that protects your blood vessels from the damaging effects of insulin.

CYP2C19 a test used to determine your availability to Plavix® which is a platelet inhibitor like aspirin.

F2-Isoprostanes Isoprostanes are valuable indicators of cell damage (oxidation) in your body. We test your F2-isoprostane concentration level because there is an association between increased concentration and coronary artery disease in adults.

Factor V Leiden Genotype a genetic test used to help your doctor determine if you are at higher risk for forming blood clots in your veins.

Fibrinogen a protein involved in the blood's clotting process and is also a marker of, inflammation. Fibrinogen can become elevated for a range of reasons.

Free Fatty Acids are a measurement of fatty acid molecules bound to albumin in the plasma.

HDL Particle (HDL-P) an important risk factor to consider in your treatment plan. Low HDL-P can be a major risk factor. Testing your HDL Particle (HDL-P) can help your doctor better predict coronary events and severity of disease.

High Sensitivity C-Reactive Protein (hsCRP) can indicate inflammation in your body as well as your blood vessels.

Homocysteine an amino acid found in the blood. Elevated concentrations of homocysteine can injure your blood vessel walls, cause blood clots, and increase your risk for heart disease and stroke.

Insulin a hormone produced by your pancreas, necessary for glucose (your blood sugar) to be used for energy.

LDL-P the actual number of LDL (bad) cholesterol particles in your blood.

Lp-PLA2 or lipoprotein associated phospholipase A2 travels in your blood, mainly with low-density lipoprotein (LDL). High concentration is linked to inflammation in the artery wall and can predict your risk of a heart attack or stroke.

Lp(a) Cholesterol (Lp(a) Mass) Lipoprotein(a), also called Lp(a), is a lipoprotein subclass and Lp(a)-cholesterol or Lp(a)-C. We test your Lp(a)-C because a high level in your blood is a risk factor for heart disease and stroke. If Lp(a) is high and Lp(a)-C is normal, there is no risk.

Myeloperoxidase (MPO) released as a defense mechanism when the artery wall is damaged or inflamed. It is a marker of oxidation and of HDL particle function.

MTHRF a gene that provides your body's instructions to make the building blocks for prortein. Specific versions of the MTHR gene may increase your risk of coronary heart disease and stroke.

NT-proBNP a hormone released from the cells o the heart muscle when you experience continued stress or strain on your heart.

PLAC® Test a test that measures the concentration of Lp-PLA2 in your blood.

Prothrombin G20210A Mutation a genetic test used to help your doctor determine if you are at higher risk for forming blood clots.

RBC Folate folate inside your red blood cells (RBC).

Small Dense LDL Cholesterol (sdLDL) small, dense LDL (bad) cholesterol particles

Vitamin B12 the B vitamin that helps your body make blood cells and maintain a healthy nervous system. We test your vitamin B12 to ensure there are no risk factors and to gather information to customize your treatment plan.

Vitamin D Long-term studies have linked vitamin D deficiency with a twofold increased risk of a heart attack. Knowing your vitamin D level can help your doctor make the right recommendations for medications and supplements.